Augusta University · PharmacologyVascular Metabolism and Redox Unit
Tohru Fukai · Augusta, Georgia
Research Focus
Dr. Tohru Fukai's lab at Augusta University studies how the metabolism of endothelial cells (the cells lining blood vessels) affects cardiovascular diseases like atherosclerosis and diabetes. By examining the balance between reactive oxygen species (ROS) and reactive nitrogen species (RNS), the lab seeks to uncover new ways to treat these diseases. The research combines advanced techniques like genetics and metabolism studies to better understand the mechanisms behind vascular health.
endothelial cellsvascular diseasemetabolismredox balancecardiovascular healthCRISPRglycolysisreactive oxygen speciesdiabetesatherosclerosis
Research Aims
4AIM 01Investigate the role of endothelial cell metabolism in regulating ROS and RNS balance.
AIM 02Determine how disrupted copper metabolism in endothelial cells contributes to vascular disease.
AIM 03Explore sex-specific differences in endothelial metabolism and its impact on cardiovascular health.
AIM 04Examine the effects of mitochondrial dynamics on endothelial function and angiogenesis in diabetic models.
Skills the Lab Values
CRISPR/Cas9cell culturemouse modelsmetabolic assaysWestern blotflow cytometryRNA sequencingmicroscopyvascular function analysisbiochemical assays
Output against the department
Publications221top 37% of dept.171st of 462
this lab
most publishedleast published
Citations15ktop 27% of dept.123rd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.