University of Virginia-Main Campus · Biomedical EngineeringPrice Neurotherapies Lab
Richard J. Price · Charlottesville, Virginia
Research Focus
Richard J. Price's research lab at the University of Virginia focuses on innovative therapies for neurological diseases like Alzheimer's disease and cerebral cavernous malformations (CCMs). The lab uses advanced techniques such as magnetic resonance imaging (MRI) and focused ultrasound (FUS) to enhance drug delivery and manipulate microglial responses in the brain. Their ultimate goal is to improve cognitive function and minimize the impact of these diseases through targeted, non-invasive treatments.
Alzheimer's Diseasecerebral cavernous malformationsfocused ultrasoundmicrogliagene therapydrug deliveryneuroinflammationCRISPRmagnetic resonance imagingneurological disorders
Research Aims
3AIM 01Develop MR image-guided FUS techniques to target microglial gene therapy for Alzheimer's disease.
AIM 02Evaluate the therapeutic effects of SHIP-1 deletion on microglial function and Alzheimer's progression.
AIM 03Implement targeted drug delivery for cerebral cavernous malformations using FUS to improve treatment efficacy.
Skills the Lab Values
focused ultrasoundMRI imagingdrug delivery systemsgene delivery techniquesCRISPR-Cas9mouse modelsimmunohistochemistrybiostatisticscell culturemolecular biology techniques
Output against the department
Publications242top 42% of dept.250th of 595
this lab
most publishedleast published
Citations9.6ktop 36% of dept.215th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.