University of Pittsburgh-Pittsburgh Campus · NeuroscienceNeurovascular Health and Injury Lab
Jun Chen · Pittsburgh, Pennsylvania
Research Focus
Dr. Jun Chen's lab at the University of Pittsburgh focuses on understanding how traumatic brain injuries (TBI) affect brain function and structure, particularly through the lens of neurovascular damage and inflammation. The lab is exploring the potential use of adiponectin, a hormone that may help protect the brain and restore function after such injuries. By studying the effects of this adipokine, the team aims to find new therapeutic strategies to reduce the impact of brain injuries on cognitive health.
traumatic brain injuryneurovascular unitadiponectincognitive impairmentneuroinflammation
Research Aims
3AIM 01Investigate the long-term therapeutic potential of adiponectin agonists after TBI.
AIM 02Examine how adiponectin receptor activation reduces acute brain damage post-injury.
AIM 03Explore the role of repair mechanisms in cognitive recovery following neurovascular injury.
Skills the Lab Values
cell culturemouse modelsRNA sequencingflow cytometryWestern blot
Output against the department
Publications1,183top 2% of dept.15th of 671
this lab
most publishedleast published
Citations32ktop 12% of dept.81st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.