University of Pennsylvania · Biomedical EngineeringMetabolic Imaging for Cancer Therapy Lab
Kavindra Nath · Philadelphia, Pennsylvania
Research Focus
Dr. Kavindra Nath's lab at the University of Pennsylvania focuses on improving cancer treatment monitoring through advanced imaging techniques. They study how targeted therapies, particularly those affecting metabolism in cancer cells, can be evaluated non-invasively. By analyzing metabolic changes in cancer cells, specifically in diffuse large B-cell lymphoma, the lab aims to provide earlier assessments of treatment effectiveness without the need for invasive procedures like biopsies.
metabolic imagingcancer therapiestargeted therapieskinase inhibitorsnon-invasive imagingdiffuse large B-cell lymphomabiomarkersmetabolomicsgene expression
Research Aims
5AIM 01Develop reliable imaging techniques to detect and monitor the efficacy of cancer therapies.
AIM 02Analyze gene expression and proteomics to identify metabolic pathways affected by treatments.
AIM 03Investigate metabolic changes induced by kinase inhibitors in cancer cells.
AIM 04Validate imaging-based biomarkers of treatment response in diffuse large B-cell lymphoma.
AIM 05Set the stage for clinical evaluation of imaging methods for monitoring cancer therapies.
Skills the Lab Values
metabolic imaging1H MRS13C MRScell culturexenotransplant modelsproteomicsmetabolomicsbiomarker analysisdata analysis using Python
Output against the department
Publications78bottom 12% of dept.525th of 595
this lab
most publishedleast published
Citations2.3kbottom 17% of dept.493rd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.