University of Pittsburgh-Pittsburgh Campus · NeuroscienceThe Stress Impact Lab
Anthony A Grace · Pittsburgh, Pennsylvania
Research Focus
Dr. Anthony A Grace's lab at the University of Pittsburgh explores how early stress impacts brain function differently in males and females. By studying rats, the lab examines how stress during critical developmental periods can lead to long-lasting changes in brain circuitry and behavior. The research aims to understand the mechanisms behind these differences to improve early interventions for psychiatric disorders that can develop later in life.
stresssex differencesneuron lossdopaminemental healthbehavioral neuroscienceperipubertal stress
Research Aims
3AIM 01Examine how PreP vs PostP stress impacts the BLA-vHipp projection in male and female rats.
AIM 02Examine how PreP vs PostP stress impacts the RE-vHipp projection in male and female rats.
AIM 03Examine how the plPFC and ilPFC regulate BLA-vHipp and RE-vHipp response to PreP and PostP stress.
Skills the Lab Values
rat modelsneuroanatomyimmunohistochemistrysurgery techniquesbehavioral assaysdata analysis in Relectrophysiology
Output against the department
Publications504top 11% of dept.73rd of 671
this lab
most publishedleast published
Citations47ktop 7% of dept.50th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.