Columbia University in the City of New York · Biomedical EngineeringCardiac Repair and Regeneration Lab
Ke Cheng · New York, New York
Research Focus
Dr. Ke Cheng's lab focuses on innovative therapies to repair heart damage caused by diseases like myocardial infarction. They investigate the use of long noncoding RNAs and exosomes derived from stem cells to enhance cardiac repair, as well as using novel delivery methods to ensure these therapies effectively target injured heart tissue. Their work blends biology, engineering, and translational medicine to optimize treatments that could potentially save lives.
cardiac repairlong noncoding RNA therapyexosomesstem cell therapymyocardial infarctiondrug deliveryplatelet interactionslipid nanoparticles
Research Aims
3AIM 01Develop lipid nanoparticles to deliver lncRNA-TARID for cardiac fibrosis treatment.
AIM 02Investigate platelet-exosome interactions for enhanced delivery to injured heart tissues.
AIM 03Assess the safety and efficacy of stem cell-derived exosome therapies in animal models.
Skills the Lab Values
cell culturemouse modelspig modelsRNA sequencingexosome isolationlipid nanoparticle formulationinjury modelingtoxicity testingin vitro assaysflow cytometry
Output against the department
Publications139bottom 29% of dept.420th of 595
this lab
most publishedleast published
Citations10ktop 35% of dept.206th of 595
this lab
most citedleast cited
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