Oregon Health & Science University · GeneticsThe Methylation Map Lab
Andrew Adey · Portland, Oregon
Research Focus
Dr. Andrew Adey's lab at Oregon Health & Science University studies how DNA methylation affects the development of mammalian cells. By using advanced techniques, they create detailed maps of how this modification changes during the growth of embryos. Their research aims to understand the roles of DNA methylation in cell fate decisions and connections to developmental diseases, making their findings important for both biology research and medical applications.
DNA MethylationMammalian DevelopmentSingle-Cell GenomicsEpigeneticsCell LineageDevelopmental BiologyIntestinal EpitheliumHigh-Throughput AssaysMultiomic Technologies
Research Aims
5AIM 01Map DNA methylation changes during mammalian development over time.
AIM 02Investigate how DNA methylation affects cell lineage commitment.
AIM 03Explore the relationship between DNA methylation and gene expression.
AIM 04Utilize multiomic technologies to study intestinal epithelial cells.
AIM 05Make large datasets publicly available for broader research collaboration.
Skills the Lab Values
Single-Cell DNA Methylation AssayRNA SequencingCell CultureGenomic Data AnalysisMolecular CloningFlow CytometryMicroscopyMouse ModelsBioinformaticsHigh-Throughput Data Processing
Output against the department
Publications156top 50% of dept.129th of 259
this lab
most publishedleast published
Citations13ktop 42% of dept.109th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.