University of California-Davis · Biomedical EngineeringObesity and Cancer Therapeutics Lab
Arta Monir Monjazeb · Davis, California
Research Focus
Dr. Arta Monir Monjazeb's lab at UC Davis focuses on understanding how obesity affects cancer treatment, specifically how it influences the effectiveness of radiotherapy. They study the mechanisms behind why obese cancer patients respond poorly to treatment, utilizing various mouse models to explore how obesity-related factors like the hormone leptin can alter cancer cell behavior and the immune response. By identifying these links, the lab aims to develop improved treatment strategies for obese cancer patients and contribute to personalized medicine.
radiotherapyobesitycancer resistanceleptintumor microenvironmentimmune responseadipokinespersonalized medicineanti-tumor immunity
Research Aims
3AIM 01Investigate the effects of obesity on the efficacy of radiotherapy in mouse cancer models.
AIM 02Explore leptin signaling as a mechanism of radiotherapy resistance in obesity.
AIM 03Test whether ablative radiotherapy can improve outcomes in obese cancer patients.
Skills the Lab Values
mouse modelsradiotherapycell cultureimmunosuppression techniquesin vivo experimentationapoptosis assaysT cell functional analysisbiochemical assaysgenetic profiling
Output against the department
Publications213top 50% of dept.297th of 595
this lab
most publishedleast published
Citations6.1kbottom 47% of dept.317th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.