Washington University in St Louis · Biomedical EngineeringNeuroblastoma Therapeutics Lab
Hanwen Zhang · Saint Louis, Missouri
Research Focus
Dr. Hanwen Zhang's lab at Washington University focuses on improving treatments for neuroblastoma, a challenging pediatric cancer. The research involves developing advanced therapies that combine novel radiopharmaceuticals to better target cancer cells while minimizing harm to surrounding tissues. By exploring high linear energy transfer (LET) agents, the lab aims to enhance treatment efficacy and optimize patient care for children suffering from relapsed neuroblastoma.
neuroblastomaradiotherapyhigh linear energy transfertheranosticspediatric cancerradiopharmaceuticalstumor imagingcellular-genomic effects
Research Aims
5AIM 01Develop new high LET therapies for neuroblastoma.
AIM 02Evaluate the efficacy of novel radiopharmaceuticals against cancer cells.
AIM 03Optimize treatment strategies using patient-derived models.
AIM 04Compare novel therapies with existing treatments.
AIM 05Advance neuroblastoma care through improved targeted radiotherapy.
Skills the Lab Values
cell culturemolecular imaging techniquesxenograft modelsDNA damage assessmentradioactive ligand developmentquantitative analysismicroscopyradiation dosimetrygenomic analysis
Output against the department
Publications227top 46% of dept.269th of 595
this lab
most publishedleast published
Citations8.0ktop 43% of dept.258th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.