University of Colorado Boulder · PhysiologySeals Cardiovascular Lab
Douglas R Seals · Boulder, Colorado
Research Focus
Dr. Douglas R. Seals' lab focuses on understanding how lifestyle interventions, like heat therapy and inspiratory muscle strength training, can improve cardiovascular health, particularly in mid-life and older adults. They investigate how these methods can lower high blood pressure and enhance blood vessel function, helping to mitigate risks for heart disease and other age-related issues. The research aims to explore both the effectiveness of these interventions and the underlying biological mechanisms involved.
systolic blood pressurevascular functionheat therapyinspiratory muscle strength trainingoxidative stressendothelial functioncardiovascular healthpostmenopausal womenexercise adherenceclinical trials
Research Aims
4AIM 01Assess the impact of passive heat therapy on blood pressure and vascular function in older adults.
AIM 02Evaluate the effectiveness of inspiratory muscle strength training compared to standard exercise in postmenopausal women.
AIM 03Investigate the biological mechanisms through which heat therapy influences cardiovascular health.
AIM 04Determine the long-term effects of these interventions on systolic blood pressure after cessation of therapy.
Skills the Lab Values
clinical trial designblood pressure measurementultrasound for flow-mediated dilationrandomized controlled trialssafety assessmentstatistical analysisbioassays for oxidative stresspersonalized exercise interventionsdata collection in human subjectsendothelial cell culture
Output against the department
Publications662top 2% of dept.7th of 286
this lab
most publishedleast published
Citations45ktop 4% of dept.12th of 286
this lab
most citedleast cited
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