University of Pittsburgh-Pittsburgh Campus · Microbiology & ImmunologyRichardson Lab
Anthony R. Richardson · Pittsburgh, Pennsylvania
Research Focus
Dr. Anthony R. Richardson's lab at the University of Pittsburgh focuses on understanding how certain bacterial skin pathogens can resist the toxic effects of naturally occurring molecules called polyamines. By researching the mechanisms behind polyamine toxicity and resistance in Methicillin-Resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes, the lab aims to discover new ways to create effective treatments for infections caused by these dangerous bacteria.
MRSApolyaminesbacterial resistanceStreptococcus pyogenestopical therapeutics
Research Aims
5AIM 01Explore how polyamines affect the growth and survival of MRSA and GAS.
AIM 02Investigate the mechanisms by which bacteria develop resistance to polyamines.
AIM 03Develop new synthetic polyamines that can effectively kill resistant bacterial strains.
AIM 04Validate the action mechanisms of synthetic polyamines against MRSA and GAS.
AIM 05Test the therapeutic potential of novel polyamines in treating skin infections.
Skills the Lab Values
cell cultureantibiotic susceptibility testingmolecular cloningsynthetic biology techniquesbacterial transformation
Output against the department
Publications99bottom 34% of dept.316th of 486
this lab
most publishedleast published
Citations4.2kbottom 32% of dept.330th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.