University of Washington-Seattle Campus · GeneticsStarita Genomics Lab
Lea Starita · Seattle, Washington
Research Focus
Dr. Lea Starita's lab at the University of Washington focuses on understanding genetic variants and their impact on human health. The lab aims to develop innovative approaches to measure how genetic mutations affect diseases, which can aid in diagnosing and treating patients more effectively. By leveraging advanced techniques like saturation genome editing and massively parallel sequencing, the lab strives to turn previously uncertain genetic variants into actionable insights for clinical practice.
genome editingvariant analysisgenetic variantsgenetic testingdisease diagnosis
Research Aims
4AIM 01Identify clinically impactful genes and appropriate assays to evaluate genetic variants.
AIM 02Perform high-quality assays on selected genes to determine the effects of variants on cell function.
AIM 03Share variant functional data using rigorous data standards for broad accessibility.
AIM 04Enable other laboratories to adopt SGE and VAMP-seq techniques through standardized protocols.
Skills the Lab Values
saturation genome editing (SGE)massively parallel sequencing (VAMP-seq)DNA manipulationcell culturebioinformatics analysis
Output against the department
Publications223top 38% of dept.99th of 259
this lab
most publishedleast published
Citations11ktop 45% of dept.117th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.