New York University · BiologySchwab Immunology Lab
Susan Ruth Schwab · New York, New York
Research Focus
Dr. Susan Ruth Schwab's research focuses on understanding how T cells exit from sites of inflammation, which is crucial for immune responses. By exploring the role of specific lipids in guiding T cell movement, her lab aims to uncover mechanisms that could prevent T cell exhaustion and improve memory responses during chronic inflammation. They utilize a novel mouse model to manipulate gene expression in a targeted manner, enabling detailed studies of T cell behavior in real time.
T cell exitinflammationimmune responsesphingosine 1-phosphatememory T cells
Research Aims
4AIM 01Investigate how S1P regulates T cell exit from inflamed tissues.
AIM 02Identify interactions between S1P and other receptors involved in T cell movement.
AIM 03Analyze changes in S1P gradients during inflammation.
AIM 04Track the fate of T cells that exit inflamed skin during the memory phase.
Skills the Lab Values
conditional gene targetinglight-inducible gene editingflow cytometrymouse modelsimmunological assays
Output against the department
Publications71bottom 20% of dept.827th of 1,033
this lab
most publishedleast published
Citations7.6ktop 49% of dept.504th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.