Michigan State University · Microbiology & ImmunologyOlive Lab
Andrew Olive · East Lansing, Michigan
Research Focus
Dr. Andrew Olive's lab at Michigan State University focuses on understanding how the immune system responds to tuberculosis (TB) infections. The lab investigates the role of specific proteins, known as GSK3a and GSK3b, in regulating immune responses during TB. The goal is to uncover new insights that could lead to better treatments and prevention strategies for this serious disease.
tuberculosisGSK3immunityIFN-gammamacrophagesT cell responsescytokinesantigen presentationhost-pathogen interaction
Research Aims
3AIM 01Investigate the mechanisms regulating GSK3a/b in IFN responses.
AIM 02Examine how myeloid GSK3a/b affects TB growth and inflammation.
AIM 03Test the impact of GSK3a/b loss on T cell responses against TB.
Skills the Lab Values
CRISPR screeningcell cultureT cell assaysgene editingflow cytometrytranscriptome analysisin vivo modelsmacrophage activationimmunological assays
Output against the department
Publications107bottom 39% of dept.296th of 486
this lab
most publishedleast published
Citations3.4kbottom 25% of dept.365th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.