Massachusetts Institute of Technology · BiologyLamason Pathogenesis Lab
Rebecca L Lamason · Cambridge, Massachusetts
Research Focus
Rebecca L Lamason's lab at MIT focuses on understanding how certain bacteria, specifically Spotted Fever Group Rickettsia, interact with their hosts to cause disease. The lab investigates the role of secreted bacterial proteins that manipulate host cell processes, aiming to unveil their complex life cycles and enhance our knowledge about tick-borne diseases. This research has the potential to lead to improved treatment and prevention strategies for these infections.
Rickettsiatick-borne diseasescell biologypathogenesissecreted proteinshost-pathogen interactionsgenetic screeningintracellular bacteria
Research Aims
3AIM 01Investigate the functions of the bacterial effector Sca4 across different cellular environments.
AIM 02Dissect the interactions and functions of novel secreted Rickettsia factors (Srfs).
AIM 03Assess the role of Sca4 in in vivo models of Rickettsia infection.
Skills the Lab Values
cell culturegenetic screeningproteomicsbioorthogonal taggingmolecular cloning microscopyCRISPRmutagenesisbiochemical assays
Output against the department
Publications48bottom 11% of dept.918th of 1,033
this lab
most publishedleast published
Citations2.0kbottom 14% of dept.893rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.