EUEmory University · Neuroscience
Johnson Neurodegeneration Lab
Erik C.B. Johnson · Atlanta, Georgia
Research Focus
Dr. Erik C.B. Johnson's research lab at Emory University focuses on understanding Alzheimer's disease, particularly the less commonly studied early-onset cases that affect individuals under 65. By comparing the biological changes in early-onset Alzheimer's with later-onset and genetically inherited forms of the disease, the lab aims to uncover specific protein alterations that characterize these conditions. The ultimate goal is to improve diagnostic tools and treatment strategies for all forms of Alzheimer's disease, tailoring them for younger patients.
Alzheimer's diseaseproteomicsbiomarkerscerebrospinal fluidearly-onset Alzheimer'sneurodegenerationpathophysiologybiological pathwaysclinical syndromestau protein
Research Aims
5AIM 01Determine protein changes in sporadic early-onset Alzheimer's disease.
AIM 02Compare these changes to those observed in late-onset and autosomal dominant Alzheimer's disease.
AIM 03Identify potential biomarkers in biofluids for cognitive decline in early-onset cases.
AIM 04Assess the implications of proteomic findings for therapeutic development.
AIM 05Enhance understanding of disease mechanisms specific to younger Alzheimer's patients.
Skills the Lab Values
proteomic analysiscerebrospinal fluid samplingbiofluid biomarker identificationmass spectrometrydata interpretationstatistical analysisresearch designtissue sample processingmolecular biology techniques
Output against the department
Publications132bottom 46% of dept.358th of 671
this lab
most publishedleast published
Citations6.5kbottom 44% of dept.374th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.