University of Arizona · PharmacologyMigraine Pain Research Lab
Frank Porreca · Tucson, Arizona
Research Focus
Dr. Frank Porreca's research lab focuses on understanding the brain circuits involved in migraine pain, a common and debilitating condition. The lab investigates how specific pathways and neuron types contribute to pain perception during migraine attacks, aiming to develop better treatments for patients who do not respond adequately to existing therapies. Through various advanced techniques, the lab explores both the genetic and physiological aspects of migraine to uncover new therapeutic targets.
migrainepain pathwaysCGRPneuropathic painbrain circuitsneuroimagingoptogeneticselectrophysiologypain behavior
Research Aims
3AIM 01Investigate the role of brain circuits in mediating migraine pain.
AIM 02Evaluate the effects of neuronal activation on pain behavior.
AIM 03Assess the plasticity of specific brain cell types during migraine attacks.
Skills the Lab Values
microscopyoptogeneticselectrophysiologycalcium imagingCRISPRanimal behavioral assaysimmunostaininggenetic manipulationdata analysisRNA sequencing
Output against the department
Publications395top 16% of dept.74th of 462
this lab
most publishedleast published
Citations28ktop 10% of dept.47th of 462
this lab
most citedleast cited
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