RURush University · Neuroscience
Cerebral Health Initiative
Konstantinos Arfanakis · Chicago, Illinois
Research Focus
Dr. Konstantinos Arfanakis leads a research lab at Rush University Medical Center focused on understanding cerebral small vessel disease, a condition that affects brain health and cognition in older adults. The lab aims to validate biomarkers that can help in diagnosing and monitoring cognitive decline and dementia associated with this disease. By studying diverse populations, including African American and Latino older adults, the team strives to improve preventative strategies and treatment options for brain health as we age.
cerebral small vessel diseasebiomarkerscognitive declinedementiaagingneurosciencecommunity health
Research Aims
4AIM 01Validate biomarkers for cerebral small vessel disease in diverse older adults.
AIM 02Investigate the relationship between biomarkers and cognitive decline.
AIM 03Conduct longitudinal assessments to enhance understanding of SVD.
AIM 04Collaborate with consortium sites to leverage shared expertise.
Skills the Lab Values
longitudinal study designclinical assessmentsMRI imagingbiomarker analysisdata collectionmachine learningautopsy studiespopulation studiesstatistical analysis
Output against the department
Publications417top 14% of dept.97th of 671
this lab
most publishedleast published
Citations18ktop 23% of dept.154th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.