Harvard University · GeneticsKennedy Epigenetics Lab
Scott G Kennedy · Cambridge, Massachusetts
Research Focus
Dr. Scott G. Kennedy's lab at Harvard Medical School focuses on understanding the role of non-coding RNAs in gene regulation and inheritance. The research primarily uses the C. elegans model to investigate how these molecules influence gene expression and contribute to the transmission of epigenetic information across generations. This work aims to uncover the mechanisms behind epigenetic processes that could be linked to various human diseases.
non-coding RNAsgene regulationC. elegansepigenetic inheritanceRNA interferencechromatintransgenerational inheritancedisease mechanismsviral defense
Research Aims
5AIM 01Investigate how non-coding RNAs regulate gene expression programs.
AIM 02Explore the mechanisms of transgenerational epigenetic inheritance.
AIM 03Identify pathways that manage chromatin states in C. elegans.
AIM 04Examine the role of non-coding RNAs in antiviral defense.
AIM 05Develop insights into the links between epigenetics and human disease.
Skills the Lab Values
RNA interference (RNAi)genetic screeningC. elegans cultivationchromatin analysismolecular cloningPCRRNA sequencingbioinformaticsmicroscopyprotein assays
Output against the department
Publications85bottom 25% of dept.195th of 259
this lab
most publishedleast published
Citations11ktop 47% of dept.123rd of 259
this lab
most citedleast cited
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