University of Iowa · PhysiologyMitochondrial Metabolism Lab
Eric B Taylor · Iowa City, Iowa
Research Focus
Dr. Eric B. Taylor's lab at the University of Iowa focuses on understanding how the mitochondrial dicarboxylate carrier influences liver metabolism, particularly gluconeogenesis, in normal physiology and during type 2 diabetes. The research aims to uncover the mechanisms behind altered metabolic processes in diabetes, which could lead to better treatments for the disease. By employing advanced genetic and metabolic tracing techniques, the lab seeks to connect mitochondrial function with liver health and disease.
gluconeogenesistype 2 diabetesmitochondrial metabolismliver physiologymetabolomics
Research Aims
2AIM 01Determine the role of the dicarboxylate carrier in hepatic gluconeogenesis in normal and diabetic states.
AIM 02Define the mechanistic regulation of dicarboxylate carrier abundance and gluconeogenic activity.
Skills the Lab Values
cell culturemouse geneticsstable-isotope metabolomic tracingproteomic analysisluciferase reporter assays
Output against the department
Publications174top 40% of dept.113th of 286
this lab
most publishedleast published
Citations11ktop 29% of dept.82nd of 286
this lab
most citedleast cited
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