University of California-Davis · BiologyThe BRCA2 Dynamics Lab
Neil Hunter · Davis, California
Research Focus
Dr. Neil Hunter's lab at UC Davis explores the critical role of the BRCA2 protein in the process of meiosis, which is how sperm and eggs are formed. The research focuses on understanding how BRCA2 functions in ensuring accurate chromosome segregation and maintaining gamete quality. His lab combines advanced genetic, genomic, and biochemical techniques to uncover the mechanisms of BRCA2 during reproductive cell division, with implications for addressing infertility and genetic disorders.
BRCA2meiosisgamete qualityDNA repairhomologous recombinationRAD51mouse modelssuper-resolution imagingChIP-Seqinfertility
Research Aims
3AIM 01Define the binding patterns of BRCA2 during meiosis using imaging techniques.
AIM 02Investigate the roles of BRCA2 at different stages of meiosis by creating gene inactivation models in mice.
AIM 03Examine how the SYCP3 protein affects BRCA2's function in meiotic recombination.
Skills the Lab Values
PCRcell culturemouse modelssuper-resolution immunofluorescenceChIP-Seqbiochemical assaysgenomic mappingmolecular biology techniqueshistological analysisdata visualization
Output against the department
Publications295top 19% of dept.196th of 1,033
this lab
most publishedleast published
Citations12ktop 31% of dept.319th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.