AECAlbert Einstein College of Medicine · Biomedical Engineering
Radiation Resilience Lab
Chandan Guha · Bronx, New York
Research Focus
Dr. Chandan Guha's lab studies how sex differences impact the body's response to radiation exposure, aiming to improve treatments for radiation injuries. They focus on how hormones and genetic factors differ between males and females and how these differences can affect health outcomes after radiation exposure. One of their key projects is developing a new drug that could help protect the intestines from radiation damage.
radiation injurysexual dimorphismmedical countermeasuresthrombopoietin mimeticgastrointestinal acute radiation syndromehematopoietic acute radiation syndromeimmune responsebone marrowmetabolomics
Research Aims
5AIM 01Investigate the impact of sex as a biological variable on radiation injury.
AIM 02Develop a thrombopoietin mimetic (TPOm) to mitigate gastrointestinal acute radiation syndrome (GI-ARS).
AIM 03Evaluate the role of gonadal hormones in radiation damage and recovery.
AIM 04Assess differences in immune response and regeneration between male and female models.
AIM 05Characterize pharmacokinetics and pharmacodynamics of TPOm in animal models.
Skills the Lab Values
PCRmouse modelsflow cytometryhistological analysisRNA sequencingdrug developmentmetabolomicsimmunohistochemistrysurvival studies
Output against the department
Publications556top 13% of dept.78th of 595
this lab
most publishedleast published
Citations11ktop 33% of dept.194th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.