Northwestern University · BiologyMetastatic Cancer Therapeutics Lab
Sui Huang · Evanston, Illinois
Research Focus
Dr. Sui Huang's lab focuses on understanding and developing treatments for cancer metastasis, which is the spread of cancer to other parts of the body. They are working on identifying unique cellular structures associated with metastatic cancer to use as markers for drug testing. One promising drug, metarrestin, has shown effectiveness in preventing metastasis in laboratory settings and is now being tested in clinical trials for pancreatic cancer. The lab aims to create more effective treatments that target these specific cancer traits without harming normal cells.
cancer metastasismetarrestintherapeutic developmentphenotypic markerseEF1A2high-content screeningxenograft modelsdrug discoveryanti-cancer agentsbiomarkers
Research Aims
5AIM 01Investigate key cellular structures associated with cancer metastasis.
AIM 02Develop new therapeutic leads targeting specific markers of malignancy.
AIM 03Explore the efficacy of metarrestin in inhibiting cancer cell invasion and metastasis.
AIM 04Identify molecular interactions with eEF1A2 for therapeutic applications.
AIM 05Conduct clinical trials to evaluate the effectiveness of metarrestin in cancer patients.
Skills the Lab Values
cell culturehigh-content screeningmouse modelsin vitro assaystumor tissue analysismolecular biology techniquesWestern blotdrug developmentDNA binding assaysphenotypic analysis
Output against the department
Publications294top 19% of dept.198th of 1,033
this lab
most publishedleast published
Citations28ktop 13% of dept.130th of 1,033
this lab
most citedleast cited
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