Washington University in St Louis · Biomedical EngineeringThe Antibody Alliance
Patricia Manuela Ribeiro Pereira · Saint Louis, Missouri
Research Focus
Dr. Patricia Ribeiro Pereira's lab focuses on improving cancer treatments, specifically for breast and gastric cancers. They are exploring innovative antibody-drug conjugates that enhance drug delivery to tumor cells, especially in cases where tumors have developed resistance to standard therapies. By using special antibody pairs that can bind more effectively to cancer cells, the lab aims to make existing treatments more effective and potentially prevent drug resistance in the future.
breast cancergastric cancerantibody-drug conjugatesdrug resistanceHER2targeted therapymolecular imagingpreclinical studies
Research Aims
5AIM 01Optimize clickable antibody-drug conjugates for better tumor targeting
AIM 02Evaluate the efficacy of antibody clickable pairs in HER2 heterogeneous tumors
AIM 03Investigate the mechanisms behind drug resistance in breast and gastric cancer
AIM 04Establish preclinical models for testing new therapeutic approaches
AIM 05Lay the groundwork for future clinical trials using innovative drug delivery methods
Skills the Lab Values
cell cultureantibody-drug conjugationanimal modelsmolecular imaging techniquesflow cytometryimmunohistochemistryspectroscopydata analysis using Python
Output against the department
Publications92bottom 15% of dept.507th of 595
this lab
most publishedleast published
Citations1.8kbottom 11% of dept.527th of 595
this lab
most citedleast cited
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