The University of Texas Health Science Center at San Antonio · GeneticsOsmulski Lab
Pawel A. Osmulski · San Antonio, Texas
Research Focus
Dr. Pawel A. Osmulski's lab focuses on understanding how cells stick to each other and their environment, which is crucial for cancer research and tissue health. The team is developing advanced technology using atomic force microscopy to measure and visualize the adhesive properties of live cells. This innovative approach aims to identify the factors that contribute to cell adhesion, especially in aggressive cancer types, to improve diagnosis and treatment strategies.
cell adhesioncancer biologyatomic force microscopytumor microenvironmentcellular interactionsbiophysical methodscancer metastasislive cell imaging
Research Aims
5AIM 01Develop a new method (MAPA) to measure the adhesion properties of live cells.
AIM 02Characterize cell adhesion in prostate cancer cells under invasion-promoting conditions.
AIM 03Test the MAPA technology with circulating tumor cells isolated from patients.
AIM 04Establish standard procedures for spectral analysis of cell adhesion.
AIM 05Investigate the relationship between cell adhesion and cancer cell invasiveness.
Skills the Lab Values
atomic force microscopy (AFM)cell culturespectral analysisbiophysical characterizationmicroscopy techniquesdata collection and analysisexperience with cancer cell linesbiomaterial testing
Output against the department
Publications136bottom 43% of dept.145th of 259
this lab
most publishedleast published
Citations2.7kbottom 14% of dept.223rd of 259
this lab
most citedleast cited
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