Johns Hopkins University · Biomedical EngineeringRadiopharmaceuticals and Cancer Metabolism Lab
Sangeeta Ray · Baltimore, Maryland
Research Focus
Dr. Sangeeta Ray's lab focuses on cancer therapies, particularly using targeted radiopharmaceuticals to improve treatment outcomes for prostate and renal cancers. By studying how glutamine metabolism influences cancer cell survival and response to radiation, the lab aims to develop innovative therapies that could enhance the effectiveness of existing treatments. Their work is crucial in understanding how to overcome resistance to radiation therapy in these prevalent cancers.
radiopharmaceutical therapyglutamine metabolismprostate cancerrenal cell carcinomaradioresistance
Research Aims
3AIM 01Evaluate the effect of PSMA-RPT on glutaminolysis as a monotherapy.
AIM 02Determine the role of pharmacological and genetic inhibition on glutaminolysis in prostate and renal cancer cell lines.
AIM 03Investigate the effects of PSMA-RPT in preclinical models of prostate and renal cancer in both immunodeficient and immunocompetent mice.
Skills the Lab Values
cell culturemouse modelsWestern blottingimmunofluorescencein vitro experiments
Output against the department
Publications42bottom 5% of dept.567th of 595
this lab
most publishedleast published
Citations297bottom 2% of dept.582nd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.