University of Rochester · BiologyFu tRNA Lab
Dragony Fu · Rochester, New York
Research Focus
Dr. Dragony Fu's lab at the University of Rochester focuses on understanding the critical roles of tRNA modification enzymes in human health. They investigate how alterations in these enzymes can lead to diseases by studying their impact on tRNA structure, function, and the regulation of cellular processes. The lab aims to build new models to study these mechanisms, with the ultimate goal of uncovering therapeutic strategies for diseases linked to tRNA modifications.
tRNA modificationsbiochemistrygeneticsdisease modelingcellular pathwaysRNA foldinggene regulationneurodevelopment
Research Aims
5AIM 01Elucidate the biological roles of tRNA modification enzymes
AIM 02Investigate how modifications affect tRNA structure and function
AIM 03Develop new disease models for studying tRNA modification
AIM 04Reveal the tissue-specific roles of tRNA modification enzymes
AIM 05Explore the potential of tRNA modifications in gene regulation and therapeutic strategies.
Skills the Lab Values
PCRmolecular cloningcell cultureRNA sequencingbiochemical assaysgenetic engineeringbioinformaticsWestern blottingCRISPR
Output against the department
Publications83bottom 26% of dept.765th of 1,033
this lab
most publishedleast published
Citations3.1kbottom 23% of dept.792nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.