University of Virginia-Main Campus · ChemistryPharmacogenomics and Neurochemistry Lab
B. Jill Venton · Charlottesville, Virginia
Research Focus
B. Jill Venton's research lab at the University of Virginia focuses on developing innovative tools for pharmacogenomic screening and understanding neuromodulation in the brain. One key project aims to create a low-cost, portable microfluidic system that can quickly analyze genetic factors influencing how patients metabolize antidepressants. Another project investigates the role of adenosine in modulating brain activity, utilizing advanced techniques to measure various neurotransmitters simultaneously. This work has the potential to improve treatment for conditions like major depression and brain injuries.
pharmacogenomicsneurochemical signalingmicrofluidicsaduinosineneurosciencedepressionreal-time monitoringneuroprotectiondrug metabolism
Research Aims
5AIM 01Develop a point-of-care system for rapid pharmacogenomic screening of depression patients.
AIM 02Create multiplexed tools for real-time monitoring of adenosine and neurotransmitter interactions.
AIM 03Determine the spatial range of adenosine neuromodulation in brain slices.
AIM 04Investigate the temporal effects of adenosine on dopamine and glutamate release.
AIM 05Advocate for the use of rapid tests to optimize drug prescribing and improve patient outcomes.
Skills the Lab Values
fast-scan cyclic voltammetry (FSCV)microfluidic device developmentgenetically-encoded sensorsmouse modelsbuccal swab analysiselectrode fabricationneurotransmitter measurementdata interpretationsignal processing
Output against the department
Publications183bottom 43% of dept.123rd of 216
this lab
most publishedleast published
Citations11ktop 44% of dept.96th of 216
this lab
most citedleast cited
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