Harvard University · Microbiology & ImmunologyJackson Immunogenomics Lab
Ruaidhri Jackson · Cambridge, Massachusetts
Research Focus
Ruaidhri Jackson's lab at Harvard Medical School focuses on uncovering the hidden complexities of the immune system's genome. The team is investigating non-coding RNAs and novel protein-coding mechanisms that play crucial roles in the inflammatory response. By using advanced techniques like ribosome profiling, they aim to redefine our understanding of gene function and discover new therapeutic targets for diseases related to immune response.
genomicsimmune systeminflammationnon-coding RNAribosome profilingchimeric proteinsgene regulationtranscriptional silencingRNA splicing
Research Aims
5AIM 01Identify and functionally characterize non-coding RNAs involved in the inflammatory response.
AIM 02Develop new techniques to detect and analyze chimeric proteins from atypical RNA splicing.
AIM 03Investigate the role of alternative open reading frames in immune response regulation.
AIM 04Assess the physiological implications of newly identified genomic elements in inflammation and disease.
AIM 05Unravel the mechanisms of RNA translation and its contribution to protein synthesis in various contexts.
Skills the Lab Values
ribosome profilinggene silencinganimal modelsRNA sequencingcell culturePCRflow cytometryWestern blotbioinformaticsmolecular cloning
Output against the department
Publications46bottom 9% of dept.442nd of 486
this lab
most publishedleast published
Citations5.5kbottom 40% of dept.291st of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.