Cornell University · BiochemistryTransposable Elements and Development Lab
Cedric Feschotte · Ithaca, New York
Research Focus
Dr. Cedric Feschotte's lab at Cornell University studies transposable elements (TEs), which are DNA sequences that can change their position within the genome. These elements are critical for understanding evolution and genetic variation, as they can influence gene expression and contribute to cellular functions. By examining the role of young TEs in human and zebrafish development, the lab aims to uncover their significance in processes like embryonic growth and pregnancy, potentially leading to new insights into diseases such as neurodevelopmental disorders and complications during pregnancy.
transposable elementsgenomicsembryonic developmenthuman healthevolutiongene regulationzebrafish modelneurodevelopmental disorderspregnancy complications
Research Aims
5AIM 01Investigate the role of young transposable elements in vertebrate embryonic development.
AIM 02Uncover the impact of TEs on gene regulatory networks involved in placenta development.
AIM 03Examine the mutualistic relationships between host organisms and transposable elements.
AIM 04Identify the mechanisms by which TEs contribute to evolutionary innovations.
AIM 05Explore the association between TEs and developmental disorders like preeclampsia.
Skills the Lab Values
genomic sequencingembryo manipulationzebrafish husbandrymolecular cloningPCRgene expression analysiscell culturebioinformaticsfunctional assaysCRISPR
Output against the department
Publications200top 41% of dept.164th of 402
this lab
most publishedleast published
Citations27ktop 13% of dept.53rd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.