University of North Carolina at Chapel Hill · BiochemistryPlatelet and Hemostasis Research Lab
Wolfgang Bergmeier · Chapel Hill, North Carolina
Research Focus
Dr. Wolfgang Bergmeier's lab at the University of North Carolina focuses on understanding how certain cellular signaling pathways influence the behavior of platelets, which are crucial for blood clotting. The research seeks to unravel the mechanisms that lead to problems like excessive bleeding or unwanted blood clots in conditions such as cancer and thrombosis. By identifying how platelets function and their role in blood diseases, the lab aims to develop better diagnostics and treatments for these critical health issues.
platelet biologythrombosishemostasisblood coagulationG proteinsintegrin receptorsantithrombotic therapybiomarker development
Research Aims
4AIM 01Investigate G protein networks and their role in platelet function.
AIM 02Explore the contribution of platelets to venous thrombosis and develop new treatment options.
AIM 03Create novel assays to assess platelet activation in various diseases.
AIM 04Study defects in platelet count and function related to genetic and acquired disorders.
Skills the Lab Values
cell culturein vivo studiesin vitro assaysflow cytometryWestern blotmicroscopymolecular biology techniquesPCRdata analysis with R/Python
Output against the department
Publications238top 32% of dept.126th of 402
this lab
most publishedleast published
Citations9.3kbottom 48% of dept.210th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.