Boston University · EngineeringCerebrovascular Health and Neurodegeneration Lab
Yanhang Katherine Zhang · Boston, Massachusetts
Research Focus
Dr. Yanhang Katherine Zhang's lab at Boston University focuses on understanding the role of cerebrovascular health in neurodegenerative diseases like Alzheimer's and the mechanical properties of arterial walls in conditions like aortic dissection. The research aims to connect changes in blood vessel structure and function with cognitive decline and disease progression, potentially leading to new diagnostic and treatment options. They employ advanced imaging and modeling techniques to study these complex interactions.
Alzheimer's DiseaseCerebrovascular ResearchAortic DissectionExtracellular MatrixBiomechanicsNeurodegenerationCardiovascular HealthVascular BiologyMechanical PropertiesCognitive Function
Research Aims
5AIM 01Investigate cerebrovascular remodeling in Alzheimer's disease brains.
AIM 02Evaluate the correlation between cerebrovascular changes and neurodegenerative pathology.
AIM 03Analyze the effects of arterial mechanical properties on aortic dissection initiation.
AIM 04Establish the relationship between local ECM structure and aortic disease progression.
AIM 05Develop predictive models for aortic dissection based on mechanical property variations.
Skills the Lab Values
Optical ImagingMass SpectrometryImmunohistochemistryBiomechanical TestingFinite Element ModelingTissue Sample PreparationData AnalysisMathematical ModelingMicroscopyCell Culture
Output against the department
Publications100bottom 22% of dept.217th of 278
this lab
most publishedleast published
Citations2.6kbottom 19% of dept.226th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.