Stanford University · EngineeringAbu-Remaileh Metabolism Lab
Monther Abu-Remaileh · Stanford, California
Research Focus
Dr. Monther Abu-Remaileh's lab at Stanford University focuses on understanding how cancer cells adapt their metabolism to survive in nutrient-poor environments. By studying the role of lysosomes in nutrient acquisition, particularly in pancreatic cancer, the lab aims to develop new technologies and models to analyze how tumors utilize nutrients. This research may lead to the identification of new therapeutic strategies to target metabolic vulnerabilities in cancer cells.
tumor metabolismlysosomesnutrient scavengingpancreatic cancermetabolic adaptationcancer therapyautophagymacropinocytosissubcellular profilingcell-type specificity
Research Aims
5AIM 01Develop innovative technologies to analyze lysosomal content in tumors.
AIM 02Investigate how cancer cells adapt their metabolism under nutrient scarcity.
AIM 03Create mouse models for studying lysosomal responses in pancreatic cancer.
AIM 04Profile metabolic changes in different tumor cell types.
AIM 05Identify new therapeutic targets based on metabolic vulnerabilities.
Skills the Lab Values
cell culturemouse modelsautophagy assaysbiochemical assaysmetabolite profilinggenetic engineeringimaging techniqueslipid analysisprotein analysisin vivo studies
Output against the department
Publications100bottom 22% of dept.216th of 278
this lab
most publishedleast published
Citations9.5ktop 38% of dept.105th of 278
this lab
most citedleast cited
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