University of Mississippi · PharmacologyRoman Lab
Richard J. Roman · University, Mississippi
Research Focus
Dr. Richard J. Roman's lab at the University of Mississippi Medical Center focuses on understanding how blood vessel health affects Alzheimer's disease and related dementias. The research explores how inhibiting specific enzymes can protect brain function and improve cognition by enhancing blood flow in the brain. This work aims to uncover new therapeutic strategies to combat these debilitating diseases.
Alzheimer's Diseasevascular healthcognitive protectionsEH inhibitorsbrain perfusion
Research Aims
5AIM 01Investigate the role of soluble epoxide hydrolase in Alzheimer's disease.
AIM 02Examine how vascular function changes affect cognitive abilities.
AIM 03Analyze the impact of sEH inhibitors on brain blood flow.
AIM 04Explore the relationship between lipid signaling and dementia.
AIM 05Develop new therapeutic strategies targeting vascular mechanisms in AD.
Skills the Lab Values
animal modelscerebrovascular function assessmentpharmacological testingtissue sample analysisbiochemical assays
Output against the department
Publications164bottom 45% of dept.251st of 462
this lab
most publishedleast published
Citations10ktop 38% of dept.175th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.