University of Southern California · BiologyLiman Taste Lab
Emily R. Liman · Los Angeles, California
Research Focus
Dr. Emily R. Liman's research lab focuses on understanding how taste receptors in mammals detect different tastes, particularly sour and salty flavors. The lab studies a specific channel called OTOP1, which plays a crucial role in sensing acids and high concentrations of salts. By exploring how OTOP1 functions, the research aims to develop new tools to enhance our understanding of taste and potentially improve dietary choices to help combat health issues like obesity and hypertension.
taste transductionOTOP1sour tasteion channelsgustatory systempH sensingdietary choicestaste receptorsbehavioral responsesobesity prevention
Research Aims
3AIM 01Identify pharmacological tools to activate or inhibit OTOP1 channels.
AIM 02Examine OTOP1's role in detecting water and carbonation in taste receptor cells.
AIM 03Investigate gustatory nerve responses and behavioral aversion to taste stimuli in mice.
Skills the Lab Values
patch clamp recordingcell culturemouse modelsgenetic knockout techniquespharmacological screeningelectrophysiologydata analysistaste behavioral assaysmolecular biology techniques
Output against the department
Publications92bottom 31% of dept.712th of 1,033
this lab
most publishedleast published
Citations7.7ktop 48% of dept.496th of 1,033
this lab
most citedleast cited
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