University of California-Los Angeles · Microbiology & ImmunologyWen HIV Lab
Jing Wen · Los Angeles, California
Research Focus
Dr. Jing Wen's lab at UCLA focuses on developing innovative solutions to combat HIV, especially in infants. They are exploring a new method to deliver broadly neutralizing antibodies (bNAbs) more effectively across the blood-brain barrier to target infections and reservoirs in the central nervous system (CNS). This research is crucial for improving treatments for infants infected with HIV and reducing neurological complications related to the virus.
HIVbroadly neutralizing antibodiescentral nervous systemnanotechnologyneuroinflammationblood-brain barrierinfant healthviral suppressionantibody therapyreservoir clearance
Research Aims
4AIM 01Evaluate the efficacy of bNAbs encapsulated in nanocapsules against CNS infections.
AIM 02Develop therapeutic strategies for suppressing HIV in CNS reservoirs.
AIM 03Explore the impact of early intervention in infants with HIV.
AIM 04Investigate mechanisms behind CNS infections and neuroinflammation during early treatment.
Skills the Lab Values
nanotechnologyantibody formulationanimal modelsbioinformaticsPCRcell cultureCNS involvement analysisviral load measurementmolecular biology techniques
Output against the department
Publications258top 22% of dept.105th of 486
this lab
most publishedleast published
Citations7.9ktop 45% of dept.220th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.