Texas A&M University-College Station · ChemistryLiu Protein Lab
Wenshe Ray Liu · College Station, Texas
Research Focus
Dr. Wenshe Ray Liu's lab at Texas A&M University focuses on innovative methods for studying proteins, particularly how they are modified after being made. By using a special technique that incorporates noncanonical amino acids into proteins, the lab explores important biological questions related to cell regulation and response to disease. Their research aims to identify how specific modifications to proteins can influence various cellular processes, potentially leading to new therapeutic strategies.
noncanonical amino acidsposttranslational modificationsprotein engineeringchromatinubiquitinationcellular signalingmass spectrometrycryogenic electron microscopyimmune response
Research Aims
5AIM 01Investigate the functions of posttranslational lysine modifications in proteins.
AIM 02Develop designer nucleosomes to study histone interactions.
AIM 03Analyze the structures of protein complexes using cryo-EM.
AIM 04Synthesize triubiquitin isoforms for proteomics studies.
AIM 05Explore the regulation of cGAS activity through lysine modifications.
Skills the Lab Values
ncAA mutagenesisprotein purificationmass spectrometrycryogenic electron microscopycell culturegenetic engineeringbioinformaticsprotein synthesisrecombinant DNA technology
Output against the department
Publications190bottom 45% of dept.119th of 216
this lab
most publishedleast published
Citations9.1kbottom 49% of dept.110th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.