Michigan State University · Biomedical EngineeringNanotech Oncology Lab
Anna Moore · East Lansing, Michigan
Research Focus
Dr. Anna Moore's lab focuses on developing innovative therapies for metastatic breast cancer using nanoparticle-based techniques. They use specially designed nanodrugs to target and inhibit specific microRNAs responsible for cancer cell survival and growth. Through research involving large animal models, the lab aims to translate these promising findings into potential treatment options for human patients.
nanomedicinebreast cancermetastasismicroRNAtheranostic nanotechnologydrug deliverycompanion animalsMRI
Research Aims
4AIM 01Develop a nanodrug to inhibit microRNA-10b in metastatic breast cancer cells.
AIM 02Test the efficacy of the nanodrug in large animal models.
AIM 03Assess the pharmacokinetics and pharmacodynamics of the drug delivery system.
AIM 04Evaluate the therapeutic outcomes in combination with low-dose chemotherapy.
Skills the Lab Values
nanoparticle synthesisin vivo imaginganimal handlingintravenous injection techniquestherapeutic drug testingtissue culturemagnetic resonance imaging (MRI)apoptosis assayschemotherapeutic combination strategies
Output against the department
Publications166bottom 37% of dept.373rd of 595
this lab
most publishedleast published
Citations8.8ktop 39% of dept.232nd of 595
this lab
most citedleast cited
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