Rowan University · BiologyTongue Development and Cancer Research Lab
Archana Kumari · Glassboro, New Jersey
Research Focus
Dr. Archana Kumari's lab at Rowan University focuses on understanding how specific signaling pathways influence the development and health of the tongue and taste organs, particularly in the context of pediatric health and oral cancer. The research includes exploring the role of Hedgehog signaling in the growth and function of the tongue, and developing new treatments for oral squamous cell carcinoma (OSCC) by inhibiting this pathway with existing drugs. Findings aim to shed light on developmental processes and improve therapeutic strategies for serious health issues related to the tongue and oral cancer.
Hedgehog signalingtongue developmentoral cancerOSCCtaste organsmorphogenesistherapeutic strategypediatric healthcell signaling
Research Aims
3AIM 01Investigate the components of Hedgehog signaling in postnatal tongue maturation.
AIM 02Assess the effect of Hedgehog pathway inhibition on OSCC cell viability and migration.
AIM 03Evaluate the synergistic effects of sonidegib with other FDA-approved drugs for improved OSCC treatment.
Skills the Lab Values
RNA sequencinggenetic mouse modelscell cultureviability assaysimaging techniquesmotility assaysmolecular biology techniquesdrug discoverybioinformatics
Output against the department
Publications87bottom 28% of dept.736th of 1,033
this lab
most publishedleast published
Citations1.1kbottom 6% of dept.975th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.