Indiana University-Purdue University-Indianapolis · Biomedical EngineeringAlzheimer's Biomarkers Research Lab
Andrew J Saykin · Indianapolis, Indiana
Research Focus
Dr. Andrew J Saykin's research lab focuses on understanding Alzheimer's disease and related dementias through a comprehensive study of brain aging. The lab collaborates on a large-scale project that collects and analyzes longitudinal clinical, genetic, and neuroimaging data from diverse populations, particularly a Korean cohort. The goal is to identify early biomarkers and improve diagnostic and therapeutic strategies for Alzheimer's disease.
Alzheimer's Diseasebrain agingneuroimaginggenomicsbiomarkersclinical datamulti-omicsKorean cohortdata sharingsystems biology
Research Aims
3AIM 01Continue collecting longitudinal clinical and biospecimen data from participants
AIM 02Analyze brain imaging biomarkers in relation to clinical data
AIM 03Integrate multi-omics data to identify gene pathways associated with Alzheimer's disease
Skills the Lab Values
MRI analysisRNA sequencingwhole genome sequencingdata harmonizationbioinformaticsstatistical analysismachine learningmultimodal data integrationethics in researchclinical trial design
Output against the department
Publications1,882top 1% of dept.6th of 595
this lab
most publishedleast published
Citations99ktop 1% of dept.5th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.