University of Missouri-Kansas City · EngineeringOsteochondral Tissue Engineering Lab
Le Yu · Kansas City, Missouri
Research Focus
Dr. Le Yu's lab focuses on developing innovative scaffolds to regenerate osteochondral tissues, which are critical for joint health. They explore how biomineralization works in the body to create materials that mimic natural tissue structures. This research aims to provide new treatment options for conditions like osteoarthritis and to improve healing in damaged joints.
biomineralizationosteochondral tissuetissue engineeringbiomimetic materialsstem cellsjoint regenerationscaffold designcartilage repair
Research Aims
3AIM 01Design and fabricate mineralized scaffolds with zonal-specific compositions.
AIM 02Evaluate mechanical properties and bonding of multizonal scaffolds.
AIM 03Assess in vitro cell differentiation and in vivo tissue formation in the scaffold.
Skills the Lab Values
biomimetic scaffold fabricationcollagen mineralization techniquescell culturetissue engineering principlesmechanical testing of materialsfluorescent imagingin vitro differentiation assayszonal-specific scaffold characterization
Output against the department
Publications234top 39% of dept.106th of 278
this lab
most publishedleast published
Citations34ktop 8% of dept.22nd of 278
this lab
most citedleast cited
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