Ohio State University-Main Campus · PhysiologyStanford Metabolism Lab
Kristin I Stanford · Columbus, Ohio
Research Focus
Dr. Kristin I. Stanford's lab at Ohio State University focuses on understanding how certain lipids, called oxylipins, can help control metabolism and combat obesity and type 2 diabetes. They employ a novel technology called tissue nanotransfection to enhance the production of a specific oxylipin, 1213-diHOME, in the body, aiming to improve energy balance and metabolic health. By exploring these mechanisms, the lab hopes to develop new therapeutic strategies to address growing public health issues related to obesity and diabetes.
obesitytype 2 diabetesoxylipinsgene deliverymetabolic health
Research Aims
2AIM 01Determine the effectiveness and efficiency of TNT-based delivery of Ephx1/2 genes into the skin to increase 1213-diHOME levels in circulation.
AIM 02Investigate the physiological effects of sustained increases in oxylipin 1213-diHOME on metabolic health.
Skills the Lab Values
tissue nanotransfectiongene delivery techniquescell cultureanimal modelsbiochemical assays
Output against the department
Publications137bottom 45% of dept.157th of 286
this lab
most publishedleast published
Citations8.3ktop 40% of dept.115th of 286
this lab
most citedleast cited
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