New York University · BiologyLung Cancer Origins Lab
Marcin Imielinski · New York, New York
Research Focus
Dr. Marcin Imielinski's lab at NYU School of Medicine researches how the original cell type from which lung cancer arises affects the disease's behavior and treatment. They focus on understanding the genetic changes that accompany lung adenocarcinoma, a common and deadly form of lung cancer. By analyzing mutations in lung cancer samples, the lab aims to identify the cell of origin for these tumors and improve diagnostic and therapeutic strategies.
lung cancercell of originpassenger mutationsgenome sequencingcancer biology
Research Aims
5AIM 01Investigate how passenger mutation patterns inform the cell of origin in lung cancer.
AIM 02Profile tumor-adjacent tissue using targeted sequencing techniques.
AIM 03Explore evolutionary trajectories of SPG mutant lung adenocarcinomas.
AIM 04Map mutational and transcriptional patterns to specific lung cell types.
AIM 05Analyze healthy lung atlases to correlate cell-specific gene expression with mutation distributions.
Skills the Lab Values
DNA sequencingsingle-cell RNA sequencingtumor profilinggenetically engineered mouse modelsbioinformatics
Output against the department
Publications267top 22% of dept.229th of 1,033
this lab
most publishedleast published
Citations68ktop 2% of dept.23rd of 1,033
this lab
most citedleast cited
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