University of Pittsburgh-Pittsburgh Campus · PharmacologyWang Lab
Qiming Jane Wang · Pittsburgh, Pennsylvania
Research Focus
Dr. Qiming Jane Wang's lab focuses on developing innovative treatments for advanced castration-resistant prostate cancer (aCRPC). The research combines targeted therapies that inhibit specific cancer cell regulators, using nanocarrier technology to deliver these drugs directly to tumors. The aim is to enhance treatment effectiveness while minimizing side effects, which is crucial for improving patient outcomes in aggressive forms of prostate cancer.
prostate cancernanocarriersCHK1WEE1cancer therapydrug deliveryepigeneticstumor targetingcombination therapy
Research Aims
2AIM 01Investigate the mechanisms of sensitivity to CHK1 and WEE1 inhibitors in aCRPC cells.
AIM 02Evaluate the safety and therapeutic efficacy of hyaluronic acid-based nanocarriers for drug delivery in prostate cancer models.
Skills the Lab Values
cell culturemouse modelsnanoparticle formulationlive-cell imagingWestern blotgenetic engineeringdrug synergy assessmentflow cytometryin vivo tumor models
Output against the department
Publications111bottom 30% of dept.323rd of 462
this lab
most publishedleast published
Citations4.4kbottom 34% of dept.307th of 462
this lab
most citedleast cited
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