Harvard University · GeneticsMetastasis Dynamics Lab
Kamila Naxerova · Cambridge, Massachusetts
Research Focus
Dr. Kamila Naxerova's lab at Harvard Medical School studies how cancer spreads, particularly focusing on colorectal cancer that metastasizes to the peritoneum. They are investigating the origins of these tumors, how different cancer cells invade the peritoneal cavity, and the genetic factors that affect patient survival. Through their research, they aim to improve treatment options for patients with this serious condition, shedding light on the genetic mechanisms behind cancer metastasis.
peritoneal metastasiscolorectal cancermetastasis founder clonesgenetic diversitytumor microenvironment
Research Aims
3AIM 01Identify how cancer cells enter the peritoneal cavity and impact genetic diversity in metastases.
AIM 02Analyze genetic characteristics of cells that successfully colonize the peritoneum.
AIM 03Investigate how genetic features of peritoneal metastases correlate with patient survival outcomes.
Skills the Lab Values
whole genome sequencingRNA sequencingphylogenetic analysispatient-derived organoidsimmunofluorescence
Output against the department
Publications119bottom 38% of dept.160th of 259
this lab
most publishedleast published
Citations6.0kbottom 32% of dept.177th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.