Purdue University-Main Campus · PharmacologyPeptide Therapeutics Lab
Jianing Li · West Lafayette, Indiana
Research Focus
Dr. Jianing Li's lab at Purdue University focuses on developing innovative peptide-based therapies for Alzheimer's Disease (AD) and related dementias (ADRD). By using advanced generative artificial intelligence (AI), the lab aims to design more effective and safer peptide drugs that can better target the causes of these diseases. The research not only seeks to improve drug development processes but also strives to make peptide therapeutics more accessible to researchers and healthcare providers.
peptide drug designAlzheimer's DiseaseADRDgenerative AItherapeuticshigh-throughputmass spectrometrydrug development
Research Aims
5AIM 01Develop generative AI models for designing peptides targeting Alzheimer's-related proteins
AIM 02Create a microdroplet-based platform for peptide selection
AIM 03Establish methods for high-throughput data generation to enhance peptide design
AIM 04Conduct in vitro and in vivo testing of AI-generated peptide candidates
AIM 05Disseminate findings to advance the field of peptide therapeutics for AD and ADRD.
Skills the Lab Values
generative AI modelingmass spectrometryhigh-throughput screeningin vitro assaysin vivo assayspeptide synthesiscell culture techniquesmicrofluidicsdata analysis
Output against the department
Publications327top 23% of dept.108th of 462
this lab
most publishedleast published
Citations7.1ktop 50% of dept.231st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.