University of Colorado Boulder · BiologyThe Cilia Nexus
Rytis Prekeris · Boulder, Colorado
Research Focus
Dr. Rytis Prekeris's lab focuses on understanding how cells maintain their structure and function, particularly in kidney cells. They study the primary cilium, a tiny organelle that helps cells sense their environment and is essential for proper kidney function. The lab investigates specific proteins that play a role in the formation of cilia and how disruptions in this process can lead to kidney diseases. Through their research, they aim to uncover the fundamental biology of cell organization and its implications for health.
ciliary biologyrenal epithelial cellsciliopathiespolycystic kidney diseasecell polarization
Research Aims
3AIM 01Investigate how TTLL12 regulates microtubule dynamics and stability.
AIM 02Explore the role of Rab19 and TTLL12 in apical cilia formation in renal polarized epithelial cells.
AIM 03Understand the mechanisms of epithelial cell polarization and cilium biogenesis during kidney development.
Skills the Lab Values
animal modelsproteomic analysismicroscopycell culture techniquesbiochemical assays
Output against the department
Publications188top 34% of dept.352nd of 1,033
this lab
most publishedleast published
Citations8.0ktop 47% of dept.484th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.