University of Nebraska at Omaha · Biomedical EngineeringKamenskiy Lab
Alexey Kamenskiy · Omaha, Nebraska
Research Focus
Dr. Alexey Kamenskiy's lab at the University of Nebraska Omaha focuses on finding innovative solutions for patients with Peripheral Artery Disease (PAD) that often leads to severe complications like amputation. The lab is developing a new method using a microneedle catheter to deliver a chelating agent called EDTA directly to calcified lesions in arteries to remove arterial calcium. This research aims not only to improve the safety and effectiveness of treatments for PAD but also to enhance the quality of life for affected individuals.
Peripheral Artery DiseaseCalcificationChelation TherapyEDTAMicroneedle CatheterBlood FlowBiomechanicsArterial HealthAnimal ModelsTranslational Research
Research Aims
5AIM 01Develop a localized method to deliver EDTA to calcified arteries
AIM 02Evaluate the effectiveness of EDTA in dissolving arterial calcification
AIM 03Assess the safety of the EDTA treatment in a preclinical model
AIM 04Investigate the impact of treatment on limb hemodynamics
AIM 05Analyze the biological response of arterial tissues after EDTA therapy
Skills the Lab Values
Microneedle catheter techniquesCalcium imagingTissue sample analysisLarge animal modelsHistological analysisBiomimetic culture systemsDrug delivery systemsStatistical analysisImmunohistochemistryDynamic hemodynamic measurements
Output against the department
Publications95bottom 15% of dept.500th of 595
this lab
most publishedleast published
Citations2.1kbottom 15% of dept.505th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.