University of California-San Francisco · BiochemistryCentrosome Research Laboratory
Jeremy F Reiter · San Francisco, California
Research Focus
Dr. Jeremy F. Reiter's lab at UCSF studies the role of centrioles—structures essential for various cellular functions—in mammalian development. Their research focuses on understanding how defects in centrioles can lead to congenital diseases, particularly affecting the heart, lungs, and inner ear. By examining how different parts of centrioles contribute to cellular functions, the lab aims to uncover critical insights into developmental processes and disease mechanisms.
centriolesmammalian developmentcongenital heart defectsciliopathiescellular cytoskeletonembryonic developmentciliogenesislung branchinginner ear development
Research Aims
3AIM 01Investigate how CEP97 promotes ciliogenesis in the heart's second heart field.
AIM 02Explore the mitotic surveillance pathway activation in lung progenitors without centrioles.
AIM 03Study the role of ALMS1 in ciliogenesis and transition zone assembly at the proximal end of the centriole.
Skills the Lab Values
mass spectrometrypan-Expansion microscopylive cell imagingmouse modelscell cultureimmunofluorescencegenetic modificationtissue dissectiondata analysis in biochemistry
Output against the department
Publications208top 38% of dept.153rd of 402
this lab
most publishedleast published
Citations18ktop 25% of dept.101st of 402
this lab
most citedleast cited
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