Loyola University Chicago · PharmacologyNeurodevelopment and Stress Resilience Lab
Monsheel S Sodhi · Chicago, Illinois
Research Focus
Dr. Sodhi's lab at Loyola University Chicago focuses on understanding how prenatal stress affects brain development and leads to differences in cognitive function between males and females. They investigate the role of RNA editing in glutamate receptors, which are crucial for learning and memory, to see how these processes differ between sexes. The ultimate goal is to identify new ways to enhance cognitive function and resilience to stress, potentially leading to improved treatments for disorders like depression and schizophrenia.
RNA editingglutamate receptorssex differencescognitive dysfunctionprenatal stresssynaptic plasticitybehavioral resiliencemental healthneurodevelopment
Research Aims
5AIM 01Investigate sex differences in cognitive deficits caused by prenatal stress.
AIM 02Determine the role of GluA2 RNA editing in enhancing stress resilience in males and females.
AIM 03Analyze synaptic plasticity and morphology in key brain regions affected by prenatal stress.
AIM 04Examine the impact of different GluA2 editing levels on spatial learning capabilities in mice.
AIM 05Assess the relationship between GluA2 editing and stress-induced behavioral changes.
Skills the Lab Values
mouse modelsRNA sequencingimmunohistochemistryWestern blotgene expression analysisbehavioral assaysneuroscience techniquespsychological stress assessmentdata collection and analysis
Output against the department
Publications59bottom 10% of dept.416th of 462
this lab
most publishedleast published
Citations2.9kbottom 21% of dept.363rd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.